Intercomparison of ozone vertical profile measurements by differential absorption lidar and IASI/MetOp satellite in the upper troposphere-lower stratosphere

This paper introduces the technique of retrieving the profiles of vertical distribution of ozone considering temperature and aerosol correction in DIAL sounding of the atmosphere. The authors determine wavelengths, which are promising for measurements of ozone profiles in the upper troposphere–lower stratosphere. An ozone differential absorption lidar is designed for the measurements. The results of applying the developed technique to the retrieval of the vertical profiles of ozone considering temperature and aerosol correction in the altitude range 6–15 km in DIAL sounding of the atmosphere confirm the prospects of ozone sounding at selected wavelengths of 341 and 299 nm with the proposed lidar. The 2015 ozone profiles retrieved were compared with satellite IASI data and the Kruger model

DIAL measurements of the vertical ozone distribution at the Siberian lidar station

The paper presents the results of DIAL measurements of the vertical ozone distribution at the Siberian lidar station. Sensing is performed according to the method of differential absorption and scattering at wavelength pair of 299/341 nm, which are, respectively, the first and second Stokes components of SRS conversion of 4th harmonic of Nd:YAG laser (266 nm) in hydrogen. Lidar with receiving mirror 0.5 m in diameter is used to implement sensing of vertical ozone distribution in altitude range of 6-16 km. The temperature correction of zone absorption coefficients is introduced in the software to reduce the retrieval errors

Deep learning-based i-EEG classification with convolutional neural networks for drug-target interaction prediction

Drug-target interaction (DTI) prediction has become a foundational task in drug repositioning, polypharmacology, drug discovery, as well as drug resistance and side-effect prediction. DTI identification using machine learning is gaining popularity in these research areas. Through the years, numerous deep learning methods have been proposed for DTI prediction. Nevertheless, prediction accuracy and efficiency remain key challenges. Pharmaco-electroencephalogram (pharmaco-EEG) is considered valuable in the development of central nervous system-active drugs. Quantitative EEG analysis demonstrates high reliability in studying the effects of drugs on the brain. Earlier preclinical pharmaco-EEG studies showed that different types of drugs can be classified according to their mechanism of action on neural activity. Here, we propose a convolutional neural network for EEG-mediated DTI prediction. This new approach can explain the mechanisms underlying complicated drug actions, as it allows the identification of similarities in the mechanisms of action and effects of psychotropic drugs

Lidar investigations of ozone in the upper troposphere – lower stratosphere: technique and results of measurements

The main aim of the research is to develop the technique for laser remote ozone sensing in the upper troposphere – lower stratosphere by differential absorption method for temperature and aerosol correction and analysis of measurement results. The authors have determined wavelengths, promising to measure ozone profiles in the upper troposphere – lower stratosphere. We present the results of DIAL measurements of the vertical ozone distribution at the Siberian lidar station in Tomsk. The recovered ozone profiles were compared with IASI satellite data and Kruger model

Lidar investigations of ozone in the upper troposphere – lower stratosphere: technique and results of measurements

The main aim of the research is to develop the technique for laser remote ozone sensing in the upper troposphere – lower stratosphere by differential absorption method for temperature and aerosol correction and analysis of measurement results. The authors have determined wavelengths, promising to measure ozone profiles in the upper troposphere – lower stratosphere. We present the results of DIAL measurements of the vertical ozone distribution at the Siberian lidar station in Tomsk. The recovered ozone profiles were compared with IASI satellite data and Kruger model

Intercomparison of ozone vertical profile measurements by differential absorption lidar and IASI/MetOp satellite in the upper troposphere-lower stratosphere

This paper introduces the technique of retrieving the profiles of vertical distribution of ozone considering temperature and aerosol correction in DIAL sounding of the atmosphere. The authors determine wavelengths, which are promising for measurements of ozone profiles in the upper troposphere–lower stratosphere. An ozone differential absorption lidar is designed for the measurements. The results of applying the developed technique to the retrieval of the vertical profiles of ozone considering temperature and aerosol correction in the altitude range 6–15 km in DIAL sounding of the atmosphere confirm the prospects of ozone sounding at selected wavelengths of 341 and 299 nm with the proposed lidar. The 2015 ozone profiles retrieved were compared with satellite IASI data and the Kruger model

Influence of Absorption Cross-Sections on Retrieving the Ozone Vertical Distribution at the Siberian Lidar Station

The purpose of this paper is to study how the application of different sets of absorption cross-sections influence the ozone vertical distribution (OVD) in the upper layers of the troposphere—stratosphere in the altitude range ~(5–45) km, using a differential absorption lidar (DIAL), operating at the sensing wavelengths 299/341 nm and 308/353 nm. We analyzed the results of lidar measurements of OVD obtained in 2021 using meteorological data from the IASI/MetOp satellite at the Siberian Lidar Station (SLS). The retrieval was performed using the data of four groups concerning the absorption cross-sections: Gorshelev et al., Malicet et al., SCIAMACHY, and GOME. To estimate how the absorption cross-sections influence the OVD retrieval from lidar measurements, we calculated the average deviations between the profiles retrieved using different sets both in a particular case on 2 January 2021 and throughout 2021. Our study showed that, out of the four absorption cross-section sets, the data of Gorshelev et al. should be used for long-term lidar monitoring of the ozone. These data show a more discrete dependence of the absorption cross-sections on the temperature values, which is more urgent for tropospheric and stratospheric ozone measurements

Influence of Absorption Cross-Sections on Retrieving the Ozone Vertical Distribution at the Siberian Lidar Station

The purpose of this paper is to study how the application of different sets of absorption cross-sections influence the ozone vertical distribution (OVD) in the upper layers of the troposphere—stratosphere in the altitude range ~(5–45) km, using a differential absorption lidar (DIAL), operating at the sensing wavelengths 299/341 nm and 308/353 nm. We analyzed the results of lidar measurements of OVD obtained in 2021 using meteorological data from the IASI/MetOp satellite at the Siberian Lidar Station (SLS). The retrieval was performed using the data of four groups concerning the absorption cross-sections: Gorshelev et al., Malicet et al., SCIAMACHY, and GOME. To estimate how the absorption cross-sections influence the OVD retrieval from lidar measurements, we calculated the average deviations between the profiles retrieved using different sets both in a particular case on 2 January 2021 and throughout 2021. Our study showed that, out of the four absorption cross-section sets, the data of Gorshelev et al. should be used for long-term lidar monitoring of the ozone. These data show a more discrete dependence of the absorption cross-sections on the temperature values, which is more urgent for tropospheric and stratospheric ozone measurements

DIAL measurements of the vertical ozone distribution at the Siberian lidar station

The paper presents the results of DIAL measurements of the vertical ozone distribution at the Siberian lidar station. Sensing is performed according to the method of differential absorption and scattering at wavelength pair of 299/341 nm, which are, respectively, the first and second Stokes components of SRS conversion of 4th harmonic of Nd:YAG laser (266 nm) in hydrogen. Lidar with receiving mirror 0.5 m in diameter is used to implement sensing of vertical ozone distribution in altitude range of 6-16 km. The temperature correction of zone absorption coefficients is introduced in the software to reduce the retrieval errors

The Impact of Freezing-thawing Process on Slope Stability of Earth Structure in Cold Climate

AbstractThe paper deals with assessment of impact of freezing-thawing process on slope stability. Numerical simulation with using coupled thermal–hydraulic–mechanical analysis (software “Geostudio 2012”, Canada) was implemented to make accurate time-dependent forecast of safety factor and defined probable slope failure mechanism of earth structures in cold climate. Results of modelling showed safety factor value was decreased from 2.15 to 1.13 when earth structure's slope is thawing. Significant increase of hydraulic gradient (from 0.1 to 14) was observed in the toe of dam